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Featured Articles

  • July 2, 2019

    Genetic Study Reveals Easily-Exploitable "Chinks in the Armor" of MRSA Superbugs

    Humans are currently locked in an arms race against pathogenic bacteria – and we're losing. After we developed antibiotics, starting with penicillin in the early 20th century, bacteria have evolved resistance to each new drug we created, threatening us with a future where antibiotics simply don't work anymore. Now scientists have identified the genes responsible for antibiotic resistance in a particularly dangerous superbug, and found a way to thwart them. Read More  

    AbbVie to Acquire Allergan for $63 Billion

    Allergan will be acquired by AbbVie for approximately $63 billion in cash and stock, the two companies announced in a press release. Under a definitive transaction agreement, which has been signed by both entities, Allergan shareholders will receive 0.8660 AbbVie shares and $120.30 in cash for each Allergan share they hold. "This acquisition creates compelling value for Allergan's stakeholders, including our customers, patients and shareholders. With 2019 annual combined revenue of approximately $48 billion, scale in more than 175 countries, an industry-leading R&D pipeline and robust cash flows, our combined company will have the opportunity to make even bigger contributions to global health than either can alone," Brent Saunders, Allergan chairman and CEO, said. Read More

    Obesity Increases Risk for Developing SSIs

    Obesity Increases a Patient’s Risk for Developing a Surgical Site Infection, or Ssi, Although the Extent of Impact Depends on the Type of Surgery, According to a Recent Study Conducted in the Netherlands. “the Prevalence of Obesity Is Growing Worldwide and Is Reaching Epidemic Proportions in Developed Countries,” Anouk P. Meijs, Msc, from the Centre for Infectious Disease Control in the Netherlands’ National Institute for Public Health and the Environment, and Colleagues Wrote. Read More

    Skin Shedding May Contribute to Spread of C. Auris

    Patients colonized with Candida auris carry a high burden of the emerging and often multidrug-resistant fungal pathogen on their skin, suggesting that the natural process of skin shedding among these patients leads to contamination of the heath care environment and contributes to transmission, according to findings presented at ASM Microbe. C. auris presents a public health concern because of its ability to cause large and persistent outbreaks, such as the outbreak in New York City hospitals. The specific mechanisms of transmission are not clear, which makes controlling these outbreaks difficult, according to Joe Sexton, PhD, a postdoctoral fellow in the CDC’s Mycotic Diseases Branch, and colleagues. Read More

  • June 25, 2019

    Atopic Dermatitis is Linked to an Increased Risk of Extracutaneous Infections

    “We have known for a long time that atopic dermatitis [AD] is associated with increased skin infections for several reasons, such as skin-barrier dysfunction, lower antimicrobial peptides, and increased bacterial colonization,” says Jonathan Silverberg, MD, PhD, MPH, director of the Northwestern Medicine Multidisciplinary Eczema Center in Chicago. But the association between AD and extracutaneous infections is not as well understood because studies have reported contrary findings. Read More  

    'Early Warning' Tool for Hard-To-Heal Leg Wounds

    Some 500,000 Australians live with the daily burden of a wound that does not heal, but a risk assessment tool that provides an 'early warning' of which venous leg ulcer wounds need specialized treatment has been developed by QUT's Dr Christina Parker. Dr. Parker's presentation on the assessment tool and its potential to help curb the $4 billion annual cost of treating chronic wounds received the top award at the CRC Association Collaborate Innovate 2019 Conference last week. "The tool is simple," Dr. Parker, from QUT's Institute of Health and Biomedical Innovation, said. Read More

    Hydrogel Offers Double Punch Against Orthopedic Bone Infections

    Surgery prompted by automobile accidents, combat wounds, cancer treatment and other conditions can lead to bone infections that are difficult to treat and can delay healing until they are resolved. Now, researchers have a developed a double-duty hydrogel that both attacks the bacteria and encourages bone regrowth with a single application containing two active components. The injectable hydrogel, which is a network of cross-linked polymer chains, contains the enzyme lysostaphin and the bone-regenerating protein BMP-2. Read More

    Manuka Honey to Kill Drug-Resistant Bacteria Found in Cystic Fibrosis Infections 

    Dr. Rowena Jenkins and Dr. Aled Roberts have found that using Manuka honey could offer an antibiotic alternative to treat antimicrobial resistant respiratory infections, particularly deadly bacteria found in Cystic Fibrosis (CF) infections. Using lung tissue from pigs, experts treated grown bacterial infections mimicking those seen in CF patients with Manuka honey. Read More

  • June 18, 2019

    Risk for Kidney Transplant Failure Quintuples with Postsurgical Diabetic Foot Ulcer

    Kidney transplantation is more likely to fail for adults with diabetic kidney disease and diabetic neuropathy who then present with a diabetic foot ulcer after surgery vs. those without foot ulcer, according to findings presented at the American Diabetes Association 79th Scientific Sessions. In addition, common factors for post-transplant diabetic foot ulcers include a prior history of the condition as well as previous peripheral arterial disease. Read More  

    Rosacea, Other ‘Mimic’ Skin Conditions Often Misdiagnosed as Rheumatic Diseases

    Patients with rosacea, livedoid vasculopathy and allergic contact dermatitis present with a multitude of dermatologic symptoms that rheumatologists can easily misdiagnose as rheumatic diseases, according to Anthony Fernandez, MD, PhD, of the Cleveland Clinic. However, he noted that rheumatologists can distinguish these dermatological conditions from their common rheumatic lookalikes — acute lupus, vasculitis and dermatomyositis — by paying attention to onset timing, chronicity and their associated symptoms. Read More

    Reimagined Hospital Bed Minimizes Risk of Pressure Ulcers

    Electrical engineering students in Arizona State University’s Ira A. Fulton Schools of Engineering completed their final capstone course with a bang. And for one team, it also ended with an award and the reward of carrying out a project that makes a difference for patients staying in hospitals. Seniors worked on a two-semester design project to fulfill all of the academic requirements for a bachelor’s degree in electrical engineering while gaining experience to prepare for the workplace. Read More

    Salamanders May Help Wound Healing: Goo Secreted by the Amphibians Sticks Injured Tissue Back Together Better Than 'Most Medical Adhesives' 

    A 'goo' given off by salamanders could revolutionize wound healing by replacing existing surgical glues. A study found the skin secretions of Chinese giant salamanders, the world's largest and longest-living amphibian, enables injured tissues to 'stick' together better than an existing 'natural' adhesive. The animals' mucus also improves skin elasticity, reduces scarring and eases side effects more than a 'chemical' glue that is currently used to repair wounds. Read More

  • June 12, 2019

    Top 7 Reasons Pressure Ulcer Rates are Still Going Up in Hospitals

    From 2014 to 2017, the overall rate of HACs had declined by 13%. Per AHRQ, 20,500 lives have been saved in that period, along with $7.7 billion in avoidable healthcare costs. In looking closer at the data, however, the rates for Pressure Injuries (PIs, also commonly referred to as Pressure Ulcers or Bed Sores) actually increased by 6% during that period. It was the only category of HACs measured that had gone up. Read More  

    Nanoscale Bioabsorbable Wound Dressing

    Scientists are harnessing the combined power of organic nanomaterials-based chemistry and a natural product found in crustacean exoskeletons to help bring emergency medicine one step closer to a viable solution for mitigating blood loss, from the hospital to the battlefield. Read More

    Atopic Dermatitis in Adults Associated with Increased Risk of Dementia

    Atopic dermatitis in adulthood was associated with a twofold increase in the risk of developing dementia late in life, based on results from a large longitudinal cohort study presented at the annual meeting of the Society for Investigative Dermatology.  Read More

    Molecular Bait Can Help Hydrogels Heal Wounds 

    Bioengineers develop modular, injectable hydrogels enhanced by bioactive molecules anchored in the chemical crosslinkers that give the gels structure. The hydrogels can be mixed at room temperature and customized to help heal a variety of wounds.  Read More

  • June 3, 2019

    Scientists Unmask Stem Cell Identity Using Gene-Sequencing Technology

    Scientists from The University of Queensland's Diamantina Institute have revealed the difference between a stem cell and other blood vessel cells using gene-sequencing technology. Leading skin cancer and stem cell researcher Professor Kiarash Khosrotehrani said the findings provided evidence of how stem cells express genes that allow them to be identified within a blood vessel. UQDI Senior Lecturer Dr Jatin Patel performed the study and looked at every single cell in the largest artery, the aorta, and identified the genes expressed by each cell through sequencing.  Read More  

    WOC Skin Health Weekly Launches Two New Surveys

    We invite all clinicians to participate in our two newest market research studies; SAWC Spring 2019 Conference Feedback, and Wound Care Brand Awareness Study. These two surveys can be found in the Active Surveys section below. Thank you for your participation.   Take a Survey

    Cellular Conflict Is Crucial to Development of Healthy Skin

    Not all cells are destined for greatness. Deemed unfit to serve in the body, some are killed off during early development through a process called cell competition. This phenomenon has previously been documented in flies and is now turning out to occur in mammals as well. In a recent study, described in Nature, Rockefeller scientists showed that skin cells in mice engage in two forms of competition, one taking place during early embryonic development and the other occurring just before birth. The researchers believe that this cutthroat cellular conflict is crucial to the cultivation of healthy skin.  Read More

    IU Researchers Develop Electroceutical Dressing to Disrupt Bacterial Biofilms 

    Work conducted in the laboratories of the Indiana Center for Regenerative Medicine and Engineering, Chandan Sen, PhD and Sashwati Roy, PhD has led to the development of a dressing that uses an electric field to disrupt biofilm infection. Their findings were recently published in the high-impact journal "Annals of Surgery." Bacterial biofilms are thin, slimy films of bacteria that form on some wounds, including burns or post-surgical infections, as well as after a medical device, such as a catheter, is placed in the body. These bacteria generate their own electricity, using their own electric fields to communicate and form the biofilm, which makes them more hostile and difficult to treat.  Read More

  • May 28, 2019

    Beating Bedsores: Researchers Working on 3D Method to Aid Treatment

    VA researchers are developing a new instrument for measuring bedsores, using 3D cameras, tablet computers, and algorithms, to help treat the problem in Veterans with spinal cord injuries. Investigators at the James A. Haley Veterans’ Hospital in Tampa, Florida, are testing an innovative computer-based system designed to more accurately measure bedsores, also known as pressure ulcers. Accurate measurement of the wound, followed by optimal treatment, is key to preventing it from worsening. Read More  

    WOC Skin Health Weekly Launches Two New Surveys

    We invite all clinicians to participate in our two newest market research studies; SAWC Spring 2019 Conference Feedback, and Wound Care Brand Awareness Study. These two surveys can be found in the Active Surveys section below. Thank you for your participation.   Take a Survey

    Extracts of Ginkgo Seeds Show Antibacterial Activity on Pathogens That Cause Skin Infections

    Extracts from the seeds of the Ginkgo biloba tree show antibacterial activity on pathogens that can cause skin infections such as acne, psoriasis, dermatitis and eczema, a study at Emory University finds. Frontiers in Microbiology is publishing the results of laboratory experiments showing that the extracts inhibit the growth of Cutibacterium acnes, Staphylococcus aureus and Streptococcus pyogenes.  Read More

    Turning and Repositioning Patients Who Are Morbidly Obese

    Pressure injuries are associated with increased length of hospital stay, high healthcare costs, and poor patient outcomes. Although many factors contribute to PI risk, morbid obesity (body mass index [BMI] > 40) is a significant and independent risk factor. Simple steps—such as turning and repositioning—that effectively reduce PI development in most patients are more challenging with patients who are obese.Barriers to adopting new technology as well as a lack of resources, training, and special equipment to aid in turning and repositioning large patients can prevent nurses and other healthcare workers from providing the best possible care. Read More