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Featured Articles

  • August 28, 2018

    Cannabis Link to Relieving Intestinal Inflammation Explained

    This is the first-time scientists have reported a biological mechanism to explain why some marijuana users have reported beneficial effects from cannabis on intestine inflammation conditions such as ulcerative colitis and Crohn's disease. Researchers hope that their findings will lead to the development of drugs and treatments for gut disorders, which affect millions of people around the world and are caused when the body's immune defenses mistakenly attack the lining of the intestine. Read More

    Fighting Lung Infection Trumps Wound Healing

    The innate immune system is responsible for responding to infections, clearing cancerous cells, healing wounds, and removing foreign substances. Although many of these functions happen simultaneously in life, most laboratory studies of the innate (or early) immune response focus on one activity. How the innate immune system responds to concurrent insults in different parts of the body is not well understood. To address this question, Dr. Meredith Crane, Dr. Amanda Jamieson and colleagues set out to determine the impact of a respiratory infection on wound healing. Read More

    Cilostazol Boosts Ulcer Healing, Amputation-Free Survival in CLI

    Cilostazol improved amputation-free survival and ulcer healing in patients with critical limb ischemia who underwent endovascular or surgical revascularization, researchers reported. The researchers conducted a retrospective, single-center cohort study to determine predictors of ulcer healing time and amputation-free survival in patients with Rutherford class 5 CLI who underwent infrainguinal arterial revascularization.  Read More

    When is Wound Cleansing Necessary and What Solution Should be Used?

    Routinely cleansing wounds at every dressing change can do more harm than good, as scrubbing the granulating wound bed with gauze swabs may disrupt fragile tissue growth and damage new capillaries. The body may perceive this as a new injury and re-launch an inflammatory response, which will only delay the healing process. Cleansing wounds is, therefore, not recommended unless the wound shows signs of infection, presents with slough or is visibly contaminated with faecal material or debris. This article explains the circumstances in which it is appropriate to cleanse a wound, when it is appropriate to use tap water and when a sterile solution is recommended. Read More

  • August 21, 2018

    Complimentary Clinical Education Webcast: "Stressing the Dressing: Reducing Vascular Access Device Complications" Featuring, Russel Nassof, JD. Wednesday, August 22nd. Space is limited.

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    Familial Hypercholesterolemia Linked to Increased PAD Risk

    Patients with familial hypercholesterolemia (FH) are at increased risk of peripheral arterial disease (PAD) and chronic kidney disease (CKD), a new prospective study confirms. Ankle-brachial index (ABI) and estimated glomerular filtration rate (eGFR) were also independently associated with risk of myocardial infarction in FH patients.  Read More

    PNF Exercises Can Help CMT1A Patients Prevent Foot Drop, Study Suggests

    Proprioceptive neuromuscular facilitation (PNF) muscle-stretching exercises can help prevent foot drop in patients with Charcot-Marie-Tooth (CMT) disease type 1A. The finding is reported in the study “Ipsilateral proprioceptive neuromuscular facilitation patterns improve overflow and reduce foot drop in patients with demyelinating polyneuropathy,” led by researchers at the University of São Paulo, Brazil, and published in the Journal of Exercise Rehabilitation.  Read More

    Experimental Drug Reverses Hair Loss and Skin Damage Linked to Fatty Diet, Shows New Study in Mice

    In a series of experiments with mice, investigators have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol. "Further research is needed, but our findings show promise for someday using the drug we developed for skin diseases such as psoriasis, and wounds resulting from diabetes or plastic surgery."  Read More

    Community Nurses ‘Under Real Pressure’ From Chronic Wound Care

    Nurses in the UK carry out 180 wound dressing changes a year on each patient with a chronic wound, a survey has indicated. It also suggested that chronic wounds, such as diabetic foot ulcers, pressure ulcers and venous leg ulcers, take more than eight months to heal for the average patient. Despite advancements in wound care, patients report dressings are changed on average five times a week, according to the survey of more than 200 people living with chronic wounds. Read More

  • August 14, 2018

    Complimentary Clinical Education Webcast: "Stressing the Dressing: Reducing Vascular Access Device Complications" Featuring, Russel Nassof, JD. Wednesday, August 22nd. Space is limited.

    Register Now

    Advanced Wound Imaging - Going Beyond 2D Photographs

    An emerging trend in wound care management is the use of connected devices such as smartphones and tablets to simplify and streamline the documentation process. Photographs of wounds taken on these devices, complete with calculated wound dimensions, can be directly added to a patient's electronic health record via specialized software and apps. Read More

    Benefits of 3D Printed Models in Vascular Surgery for Planning, Training and Patient Education

    Recent studies have shown the advantages of 3D printing for simulation of vascular surgery includes significant reduction of procedural time, but the applications of producing life-sized 3D models can have important educational benefits beyond the operation planning stage.  Read More

    Material Could Offer ‘Smarter’ Wound Healing

    A new study takes a step toward the development of smarter skin grafts that facilitate healing while minimizing infection for chronic skin wounds. “Our group has expertise in developing new polymers and functional surface assemblies for biomedical applications,” says Svetlana Sukhishvili, professor and director of the soft matter facility at Texas A&M University. Read More

    The Medicine of the Future Against Infection and Inflammation?

    Researchers have mapped how the body's own peptides act to reduce infection and inflammation by deactivating the toxic substances formed in the process. The researchers believe their discovery could lead to new drugs against infection and inflammation, for example in wound healing. Read More

  • August 7, 2018

    Three-Minute Thesis: Healing Diabetic Wounds: A Team Approach

    “Every 20 seconds, a limb is amputated because of complications in the delayed healing of chronic diabetic wounds. Understanding the mechanisms behind this delayed healing is key to developing therapies to encourage better healing and prevent the needless loss of limbs to diabetes. This project explores the link between diabetic healing and the decreased presence of a specific cell type, the pericyte, and whether targeting pericytes represents a promising avenue for the treatment of diabetic wounds.”  Read More

    Striking a Balance Between Immunity and Inflammation

    Hookworms infect people mostly in countries where sanitation is poor and people often walk barefoot. Working on a mouse model, a research team has studied the secretion of the immune protein RELMalpha that is triggered in the body, following infection, to protect body tissue. When the researchers knocked out RELMalpha, the mice produced super-killer macrophages that attached to the hookworm in far greater numbers. These macrophages, however, provoked increased tissue damage and inflammation. Read More

    Here’s Why Wounds Heal Faster in the Mouth Than in Other Skin

    Mouth wounds heal faster than injuries to other parts of the skin, and now scientists are learning how the mouth performs its speedy repairs. Some master regulators of gene activity work overtime in the mouth to heal wounds without scarring, researchers report July 25 in Science Translational Medicine. Those regulators — proteins known as SOX2, PITX1, PITX2 and PAX9 — are active in skin cells called keratinocytes in the mouth, but not in skin cells from the arm.  Read More

    Oxygen Therapy: Calls for More Funding Amid Rising Use

    Meet the Tokoroa man who has installed a hyperbaric chamber at home to help his wife's recovery from a stroke. Ian Stewart is championing the use of a treatment involving pressurised oxygen by calling for better access and funding for an increased number of treatments. The treatment involves patients lying inside a pressurised chamber and breathing pure oxygen. In a pressurised environment your lungs can take in more oxygen than would be possible at normal air pressure, which then stimulates growth and healing. Read More

  • July 30, 2018

    Machine Learning Improves Early Accurate Detection of Lymphedema

    Lymphedema, an adverse effect of breast cancer treatment that causes swelling in the arms or legs, occurs in more than 41% of patients within 10 years of their surgery. According to a new study published in mHealth, researchers have developed an efficient way to detect lymphedema with machine learning, a type of artificial intelligence. Lymphedema can be a debilitating adverse effect of breast cancer treatment that can progress to a severe and chronic condition if left untreated. There is no cure for lymphedema, but early detection and treatment can help reduce symptoms and keep it from worsening.  Read More

    Negative Pressure Wound Therapy No Better Than Standard Care For Open Traumatic Wounds

    For open traumatic wounds involving fracture or soft tissue, there is "no clear difference" between standard care and negative pressure wound therapy (NPWT), and the latter is unlikely to be cost-effective, according to a recent Cochrane Review. Four studies on open-fracture wounds found no clear difference between NPWT and standard care. After pooling data on wound infection from four studies of 596 participants with an average follow-up of 30 days, the authors concluded, "It is uncertain whether NPWT at 125 mmHg reduces the risk of wound infection (in open-fracture wounds) compared with standard care (RR, 0.48)," with very low-certainty evidence. Read More

    Immune Cells Produce Wound Healing Factor, Could Lead to New IBD Treatment

    Specific immune cells have the ability to produce a healing factor that can promote wound repair in the intestine, a finding that could lead to new, potential therapeutic treatments for inflammatory bowel disease (IBD), according to a new research study. The research team, led by Georgia State University and the University of Michigan, wanted to understand how a wound heals in the intestine because in IBD, which includes Crohn's disease and ulcerative colitis, damage to the intestinal epithelial barrier allows bacteria in the intestine to go across the barrier and stimulate the body's immune system.  Read More

    Spider Silk Could Be Used to Create Artificial Skin to Help Heal Wounds

    Researchers from Sweden and India have come up with yet another novel use for spider silk’s unusual mix of strength and elasticity: Creating artificial skin and wound dressings for helping heal wounds. “We have developed two types of silk-based constructs: Nanofibrous matrices which serve as bioactive wound dressings, and microporous sponges cultured with human skin cells to serve as artificial skin. Read More

  • July 23, 2018

    Diabetes Doubles Risk for Hospital Acquired Foot Ulcers

    Patients with diabetes have at least double the risk for developing hospital-acquired foot ulcers vs. those without diabetes, according to a study published in BMJ Open Diabetes Research & Care. Patients included in the analysis were aged at least 50 years and developed a hospital-acquired foot ulcer at least 48 hours after hospital admission. For all admissions, the analyses included data on diabetes, heel ulcer, length of stay and other covariates. Read More

    Pioneering Bandage Speeds up Wound Healing in People With Diabetes

    A bandage that could speed up the healing process of foot sores among people with diabetes has been developed. The bandage device, created by researchers at Northwestern University in Illinois, uses the body's own healing ability without the use of drugs or other pharmaceutical products. When tested, the treatment was found to heal diabetic wounds 33% faster when compared with regular bandages.  Read More

    Roundtable Discussion: Tailored Approaches to Venous Ulcers

    Experts discuss the EVRA trial and its applicability to practice, diagnosis of venous ulcers, wound care management and interaction with wound care specialists, treatment of concomitant deep and superficial disease and perforators, and future directions. Read More

    Smart Bandage Can Dispense Drugs, While Keeping An Eye On Your Wound

    The next time you cut your finger and need wound care, stitches and a bandage, wouldn’t it be reassuring to know that your wound is being monitored for signs of infection--and if you need antibiotics, they will automatically be dispensed by the bandage itself? Sounds like this is a futuristic concept, but this may soon be how you and your health care provider manage your cut, receiving data in a continuous feedback loop that lowers the chance of a wound infection--not to mention reduces the need to make an office or clinic visit for a wound check. Read More