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Featured Articles

  • October 18, 2018

    Acting Fast Is Key with Necrotizing Fasciitis

    Necrotizing fasciitis is a bacterial infection of the tissue under the skin that surrounds muscles, nerves, fat, and blood vessels. The bacteria most commonly get into the body through a break in the skin. Once in the body, the bacteria spread quickly and destroy the tissue they infect. Media reports often call them “flesh eating bacteria.” Unfortunately, necrotizing fasciitis can result in a loss of limbs and even death. Accurate diagnosis, rapid antibiotic treatment, and prompt surgery are important to stopping this infection. Read More

    UTA Researchers Patent Technology for Smart Seat Cushion, Adaptable Prosthetics

    The University of Texas at Arlington has patented a smart seat cushion that uses changes in air pressure to redistribute body weight and help prevent the painful ulcers caused by sitting for long periods of time in a wheelchair. The same technology can be used to create prosthetic liners that adapt their shape to accommodate changes in body volume during the day and maintain a comfortable fit for the prosthesis. Poor prosthetic fit can cause skin damage and create sores in the residual limb of the wearer. Read More

    Photoactive Bacteria Bait May Help in Fight Against MRSA Infections

    Purdue University researchers are testing whether a simple light-emitting diode array that is safe to use on human skin can be used to inactivate methicillin-resistant Staphylococcus aureus, or MRSA, one of six 'high priority' pathogens that the World Health Organization has identified as an imminent threat to public health. Here the light shines above a 96-well plate in a bio-safety hood. Read More

    Diabetic Foot Disease

    Diabetic foot disease is a severe complication of neuropathy and/or peripheral vascular disease and can lead to chronic infection, foot ulcers, gangrene, and lower-limb amputation. Every year, about 1% to 4% of people with diabetes develop a new foot ulcer. A foot ulcer is the initial event in more than 85% of amputations performed on those with diabetes. Although the rate of foot and leg amputation has greatly declined over the past 2 decades, increasing awareness is essential because diabetes is the leading cause of lower-limb amputations in the United States. Read More

  • October 10, 2018

    Calcipotriol Ointment Seen to Improve Wound Healing in RDEB Patient, Study Finds

    A low dose of calcipotriol, which is already approved for the treatment of psoriasis, may improve healing and prevent wound infections in patients with recessive dystrophic epidermolysis bullosa (RDEB), a study showed. Read More

    Ginsenoside Rb1 Enhances Keratinocyte Migration by a Sphingosine-1-Phosphate-Dependent Mechanism

    The cutaneous wound healing process is tightly regulated by a range of cellular responses, including migration. Sphingosine-1-phosphate (S1P) is a signaling lipid produced in keratinocytes (KC) and it is known to stimulate skin wound repair through increased KC migration. Of the multifunctional triterpene ginsenosides, Rb1 enhances cutaneous wound healing process by increasing KC migration, but cellular mechanisms responsible for the Rb1-mediated increase in KC migration are largely unknown. Therefore, we hypothesized that, and assessed whether, Rb1 could stimulate KC migration through S1P-dependent mechanisms. Rb1 significantly increases S1P production by regulating the activity of metabolic conversion enzymes associated with S1P generation and degradation, sphingosine kinase 1 (SPHK1) and S1P lyase, respectively, in parallel with enhanced KC migration. Read More

    The Role of Saline Irrigation Prior to Wound Closure in the Reduction of Surgical Site Infection: Protocol for a Systematic Review and Meta-Analysis

    Surgical site infection describes an infectious complication of surgical wounds. This single complication is thought to occur in close to 20% of surgical cases. This complication has been described in all kinds of surgical procedure including minimally invasive procedures. Wound irrigation is frequently used as a means of reducing surgical site infection. However, there is lack of solid evidence to support routine wound irrigation. The aim of this review is to provide evidence for the efficacy of routine wound irrigation with normal saline in preventing surgical site infection. The rate of surgical site infection in cases with and without wound irrigation will be analyzed. Read More

    Effect of Perioperative Oral Management on the Prevention of Surgical Site Infection After Colorectal Cancer Surgery

    Surgical site infection (SSI) is 1 of the frequent postoperative complications after colorectal cancer surgery. Oral health care has been reported to reduce the risk of SSI or postoperative pneumonia in oral, esophageal, and lung cancer surgeries. The purpose of the study was to investigate the preventive effect of perioperative oral management on the development of SSI after a major colorectal cancer surgery. Read More

  • October 2, 2018

    Hospital Privacy Curtains Harbor Infectious Bacteria

    Patient privacy curtains in hospitals became increasingly contaminated with pathogens and most tested positive for MRSA after 21 days of being hung, according to findings published in the American Journal of Infection Control. "Since hospital patient privacy curtains can harbor bacteria, are high-touch surfaces and are cleaned infrequently, they may be involved in pathogen transmission,” Kevin Shek, BSc, from the University of Manitoba, Canada, and colleagues wrote. Read More

    Atherectomy Successful in PAD; Patency Rates Similar Among Device Types

    Patients with occlusive lower extremity peripheral artery disease treated with atherectomy devices had over 96% procedural success, according to data presented at TCT 2018. When the researchers compared results by atherectomy device type, excisional atherectomy was associated with higher rates of vessel dissection and perforation and lower amputation rates compared with laser or orbital atherectomy, although long-term vessel patency was similar in all groups. Read More

    Three Factors that Predict Life-Threatening Respiratory Disease in Burn Patients

    For the first time, researchers have devised a model to predict burn patients who are most likely to develop life-threatening acute respiratory distress syndrome (ARDS). The prediction model includes three factors: the extent of the patient's inhalation injury, the percentage of the patient's body that was burned and whether the patient had high levels of a blood clotting protein called von Willebrand factor. Read More

    Use of Continuing Education to Increase Nurses' Knowledge of Chronic Wound Care Management

    Providing effective management of chronic wounds can be a major challenge for nurses practicing in health care systems. As the older adult population continues to increase, the prevalence of chronic health-related diseases that can lead to chronic wounds has also increased. Nurses have reported a lack of preparation in the management of chronic wounds. Read More

  • September 25, 2018

    Immediate Compression Offers 'Clear Benefit' Following Blood Clot

    Patients with deep vein thrombosis who underwent immediate compression therapy had significantly lower rates of residual vein obstruction and post-thrombotic syndrome than those who received no compression, according a multicenter prospective study. Read More

    Hospitals Could Reduce HAIs by up to 55%

    A large systematic review and meta-analysis showed that hospitals could reduce health care-associated infections, or HAIs, by 35% to 55% with systematic implementation of evidence-based infection prevention and control measures. Read More

    Height May be Risk Factor for Varicose Veins

    The taller you are, the more likely you are to develop varicose veins, according to a study led by Stanford University School of Medicine researchers that examined the genes of more than 400,000 people in search of clues to what causes this common but little understood condition.
    Read More

    Researchers Patent Technology for Smart Seat Cushion, Adaptable Prosthetics

    Researchers have patented a smart seat cushion that uses changes in air pressure to redistribute body weight and help prevent the painful ulcers caused by sitting for long periods of time in a wheelchair. The same technology can be used to create prosthetic liners that adapt their shape to accommodate changes in body volume. Read More

  • September 19, 2018

    Why Wound Healing Gets Harder As We Age

    When you skinned your knee as a kid, the scrape healed on its own with little more than a bandage and mom's TLC. Now that you're older, wounds can take much longer to heal — sometimes many months. "The body's capacity to repair the skin diminishes as we get older. There aren't as many growth factors and stem cells in the skin. Chronic disease, especially blood vessel disease, and malnutrition can also slow the healing process," says Dr. Dennis Orgill, a surgeon and medical director of the Wound Care Center at Harvard-affiliated Brigham and Women's Hospital. Read More

    Scientists Trial An Unexpected Source To Help Heal Hard-To-Treat Skin Injuries

    Scientists have revealed how proteins in menstrual blood can be used to stimulate skin repair, including wounds that otherwise recover poorly. Today, tens of billions of dollars are spent on chronic skin injuries, and increasing rates of diabetes are adding to this demand, so utilizing the womb's incredible ability to repair itself quickly could be the way forward. Read More

    Evidence-based Strategies Lead to Research Poster Win

    Protecting patients from pressure injury takes a team representing all players in surgical care to follow the safest evidence-based practices.
    Read More

    OIG to Investigate CMS Oversight of Skilled Nursing Staffing Measures

    The Department of Health and Human Services (HHS) Office of the Inspector General (OIG) announced that it will launch a probe into the way skilled nursing facilities maintain their staffing records — with a focus on the Centers for Medicare and Medicaid Services’ (CMS) oversight of those requirements. Read More

  • September 12, 2018

    Utilization of Arteriovenous Grafts Secondary to Fistula Failure in Patients on Dialysis

    Improvement of the clinical practice guidelines for chronic hemodialysis patients has become a priority for CMS.1,2 The use of an arteriovenous fistula has become widely endorsed as the optimal vascular access device. The other two commonly used access modalities include an arteriovenous graft and a central venous catheter. Read More

    True Multidisciplinary Approach Essential for Limb Preservation

    To prevent amputation, physicians must assemble a comprehensive multidisciplinary team to care for patients at risk for losing their limbs, Ramon Varcoe, MD, MBBS, MS, FRACS, PhD, said at AMP: The Amputation Prevention Symposium. A multidisciplinary approach to limb preservation begins with recognizing the major drivers of amputation. The global public health threat posed by the “tsunami of diabetes,” for instance, is a significant problem, he said. Read More

    Behavioral Treatment Reduces Urinary Incontinence

    A new group-administered behavioral treatment program was safe, cost-effective, reduced urinary incontinence frequency and severity, and improved quality of life among older women, according to a study published in JAMA Internal Medicine. “Urinary incontinence guidelines recommend behavioral interventions as first-line treatment using individualized approaches,” Ananias C. Diokno, MD, from the department of urology at Beaumont Hospital, Michigan, and colleagues wrote. “A one-time, group-administered behavioral treatment could enhance access to behavioral treatment.”  Read More

    One-Third of Orthopedic Trauma Patients Did Not Meet New CDC SSI Definition

    Patients with early vs late infection were not significantly different other than the need for flap coverage. About one-third patients at a level 1 trauma center did not meet the CDC definition for acute postoperative infection following fracture fixation, a presenter at the American Academy of Orthopaedic Surgeons Annual Meeting said. The CDC in 2016 changed the timeframe of its the definition of deep surgical site infections (SSIs) from within 1-year of the initial surgery to within 90 days of the initial surgery. Read More