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Featured Articles

  • October 17, 2016

    NASA Invents 'Electric Gauze' That Can Speed Up Wound Healing

    One method to facilitate wound healing is a new electric gauze recently announced by NASA. The thin material displays some mind-blowing properties, by generating a small amount of electricity when interacting with another surface, including human skin. The material, called polyvinylidene fluoride (PVDF) has numerous possible applications, including wound healing. It is proven that wounds tend to heal much more quickly if small amounts of electricity are applied to the surrounding tissue. But the gauze pattern is also essential to the healing process. Read More

    Cold Microwave Plasma Helps Cure Non-Healing Wounds

    A new study suggests that a course of cold microwave argon plasma treatments can increase the proliferation of human fibroblasts and keratinocytes. Cold plasma acts through the combination of a therapeutically relevant electrical field, low irradiation in the beneficial ultraviolet (UV) UV-A and UV-B wave length range, and activated gas particles from ambient air. The result is a deep-stimulation of the treated skin and wound surfaces. Read More

    Understanding Peripheral Arterial Disease (PAD) and Wound Care Treatment 

    Peripheral arterial disease (PAD) is a condition that develops when the arteries that supply blood to the internal organs, arms and legs become completely or partially blocked as a result of atherosclerosis. There are many possible side effects of atherosclerosis including angina and heart attacks if the coronary arteries are involved; strokes and transient ischemic attacks if the carotid and vertebral arteries are involved; and claudication, non-healing leg ulcers and critical limb ischemia if the lower extremity arteries are involved. Read More

    Research Findings Raise Hope for Better Treatment of Diabetic Wounds

    Diabetics often have to contend with wounds that heal poorly. Researchers have now gained fresh insights into the underlying cellular mechanisms. Their findings could lead to the development of new treatment methods. Parisa Kakanj, the author of the study, examined the skin of larvae of the fruit fly Drosophila melanogaster. These flies serve as models for diabetes, because insulin metabolism has been strongly conserved over the course evolution, meaning that flies and mammals are very similar in this respect. Read More

  • October 10, 2016

    Scleroderma Study Identifies Risk Factors for PAH Development

    Researchers have identified risk factors of pulmonary arterial hypertension (PAH) in patients with Scleroderma, showing that the risk profiles differ between patients with limited and diffuse cutaneous Scleroderma. The study was published in the journal BMC Pulmonary Medicine. It suggests that the findings should be implemented in screening programs, allowing early identification of patients who are at risk, especially since PAH is the leading cause of mortality among patients with Scleroderma.  Read More

    The Self-Healing Needle: Device Inspired by MUSSELS Plugs its Own Puncture Wound After an Injection

    It may not be enough to remove the fear some of us have of needles, but now scientists have invented a hypodermic syringe which seals the hole it leaves behind after it is removed. The needle coated in a film physically plugs the gap left in a vein when it is removed. The breakthrough could help prevent a vast range of problems caused by bleeding under the skin.  Read More

    Diabetes: New Hope for Better Wound Healing 

    It had previously been assumed that high levels of glucose in the blood damages vessels and neurons and impairs the immune system, thereby accounting for the wound-healing problems. A Cologne-based research group headed by Linda Partridge, Director of the Max Planck Institute for Biology of Ageing, and Maria Leptin, professor at the Institute of Genetics of the University of Cologne, has now presented in a study that slowed insulin metabolism at the wound site directly affects neighboring cells involved in wound healing. Read More


  • October 3, 2016

    Cause of Crohn's Disease: Gut Fungus Now Suspected

    People with the inflammatory condition Crohn's disease may have a higher level of a certain fungus in their gut, a new study finds. Scientists have known that gut bacteria may contribute to the development of Crohn's, but the new study finds that this fungus may also play a role in the condition. The findings could lead to new treatments for people with the disease, who may have such symptoms as severe abdominal pain, weight loss, fatigue and diarrhea. Read More

    Self-Adhesive Dressing Generates Electrical Current that Promotes Healing, Reduces Infection Risk

    Good news for the millions of people who suffer from skin wounds that won't heal. A team of researchers at The Ohio State University has brought a potentially transformative solution to the problem by creating a portable adhesive patch that drives a continuous, small electrical current to stimulate healing and reduce the risk of infection. The patch's design significantly advances existing FDA-approved wireless electroceutical dressing (WED) that harnesses the body's innate response to injury to help wounds heal. Read More

    Ganglioside GM3 Synthase Depletion Reverses Neuropathic Pain and Small Fiber Neuropathy in Diet-Induced Diabetic Mice 

    These studies establish ganglioside GM3 as a new candidate responsible for neuropathic pain and small fiber neuropathy in diabetes. Moreover, these observations indicate that systemic or topically applied interventions aimed at depleting GM3 may improve both the painful neuropathy and the wound healing impairment in diabetes by protecting against nerve end terminal degeneration, providing a disease-modifying approach to this common, currently intractable medical issue. Read More


  • September 26, 2016

    Basics of the Foot Examination

    Sadly, patients with diabetes account for 60% of all non-traumatic lower limb amputations. Many foot ulcers are preventable. Rates of amputation can be decreased by providing foot care education, preventive measures, treatment of foot problems and, if indicated, a referral to a podiatrist. A foot exam is a straightforward and inexpensive way to detect wounds, loss of sensation and other abnormalities that may cause complications. Read More

    Recognizing Non-Healing Wounds Can Prevent Serious Complications

    As a vascular surgeon, foot ulcers and poorly healing wounds are a common yet challenging condition that requires my immediate attention. If untreated, or if treatment is delayed, complications such as severe infection, gangrene, or limb loss can occur. This is true even in the early stages if not treated by a specialist. Recognizing the early warning signs and knowing when to seek help is paramount in avoiding catastrophic complications that are all too common. Read More

    Cacao Could be Used In Wound Treatment, Adelaide Researchers Find 

    Adelaide researchers are looking at taking advantage of cacao as a natural alternative to toxic chemicals traditionally used to produce wound treatments."If you use toxic chemicals they will kill not only the bacteria, but also they would kill normal tissue, but basically you can get in a worse position than you started in," Professor Vasilev said. Read More

    Nurses Win Honor for "Unique Skin Care Regime" 

    The team was praised for the education and learning value that their research provided to other health professionals and the enhanced quality of care for patients with this type of skin damage. The skin integrity nurses explored the development of a new single skin care regime for both superficial pressure ulcers and incontinence associated dermatitis. Read More

  • September 19, 2016

    Ask the Treatment Expert About ... Eschar

    A question that frequently arises is this: Exactly how is one to treat heel pressure injuries if they are covered with hard, black, dry eschar? The first intervention one should implement is pressure redistribution. This is accomplished by using pillows, positioners or devices to "float the heels" - in other words, heels are not in contact with any surface. Read More

    Scientists Find Way to Treat Non-Healing Wounds With Cold Plasma

    Open (chronic) wounds affect 5.7 million patients and cost an estimated 20 billion dollars annually. Patients with chronic wounds often find them to be not only costly but an impediment to daily life that can impact their physical and mental well-being. Existing treatments, such as Topical Negative Pressure, which requires a uniform negative pressure to the base of the wound sometimes using a vacuum, can be both expensive and uncomfortable for patients. Read More

    Topical Insulin Appears Viable in Treatment of Pressure Ulcers 

    Nursing home residents sometimes develop pressure ulcers, especially if they have low serum albumin levels, are incontinent, have fragile skin, or are bed-bound. Pressure ulcers are notoriously difficult to treat, and have systemic repercussions if they do not heal. Normal wound healing progresses from hemostasis, to inflammation, granulation, and maturation. Read More

  • September 12, 2016

    Can a Spray-On Plaster Help to Heal Chronic Wounds?

    Initial results from tests on mice published last month (August), show the spray-on dressing reduces the time it takes to achieve 50 percent closure of the wound from 17 days to just 11 days. And after 24 days, the wounds were completely healed, whereas wounds dressed with normal bandages take at least another week. Previous research has shown that up to 40 percent of diabetic ulcers take at least three months to mend and in around 14 percent of cases wounds are still present after a year. Read More

    Fungi Contribute to Delayed Healing of Chronic Wounds

    Researchers in Pennsylvania and Iowa have discovered that fungal communities found in chronic wounds can form mixed bacterial-fungal biofilms and can be associated with poor outcomes and longer healing times. Their report, the first deep characterization of the fungi found in diabetic foot ulcers, is published this week in mBio, an online open-access journal of the American Society for Microbiology. Read More

    Umbilical Cord is Shown to Help Chronic Wounds Heal

    Cryopreserved umbilical cord, or CUC, allografts healed nearly 80% of chronic wounds in a retrospective review of a Texas veterans clinic. Researchers examined the charts of 57 patients with 64 chronic wounds, and principal investigator, podiatrist Mark Couture, debrided the wounds in his clinic or in an operating room, then placed the cUC directly over the wound bed and secured it with a non-adherent layer and moist gauze or sterile dressing. Additional debridement and cUC were given, if needed, weekly. Read More