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Platelet-rich plasma, or PRP, appears to yield healing in ulcers as it changes the matrix metalloproteinase and cytokine expression shortly after topical application, according to researchers. “These articles demonstrate that topical activated PRP or autologous leukocyte- and platelet-rich fibrin applied once to twice a week for 3 to 6 weeks improves wound healing and support a standardized treatment regimen for PRP in chronic ulcers,” Michael J. Hesseler, MD, of the department of dermatology at University of Michigan, and colleagues wrote.Read More
Johns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be associated with other inflammatory skin disorders as well as systemic and mental health disorders. Compared with other skin diseases, however, not much is known about PN. While symptoms of PN can be managed, no cures exist. Researchers were looking to determine associated conditions that are more common in patients with PN. Read More
Preventing pressure ulcer formation begins with a thorough examination of the patient in order to identify the risk factors for the individual, which then allows the clinician to implement effective prevention strategies. The adage “an ounce of prevention is worth a pound of cure” is most appropriate when applied to pressure injuries/ulcers. Studies have shown that pressure ulcers (PU) increase the hospital length of stay approximately 8 days. Approximately 2.5 million persons in the US are affected by PUs each year, with the following cost statistics: “Pressure ulcers cost $9.1-$11.6 billion per year in the US. Read More
As the global demand for tissue and organ transplants significantly outstrips supply, tissue engineering might provide a potential solution. But one of the significant challenges in tissue engineering is growing tissue in 3D, and the scaffolds used to position cells to develop tissue-specific functions are often challenging or prohibitively expensive to develop. Read More