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“We have known for a long time that atopic dermatitis [AD] is associated with increased skin infections for several reasons, such as skin-barrier dysfunction, lower antimicrobial peptides, and increased bacterial colonization,” says Jonathan Silverberg, MD, PhD, MPH, director of the Northwestern Medicine Multidisciplinary Eczema Center in Chicago. But the association between AD and extracutaneous infections is not as well understood because studies have reported contrary findings. Read More
Some 500,000 Australians live with the daily burden of a wound that does not heal, but a risk assessment tool that provides an 'early warning' of which venous leg ulcer wounds need specialized treatment has been developed by QUT's Dr Christina Parker. Dr. Parker's presentation on the assessment tool and its potential to help curb the $4 billion annual cost of treating chronic wounds received the top award at the CRC Association Collaborate Innovate 2019 Conference last week. "The tool is simple," Dr. Parker, from QUT's Institute of Health and Biomedical Innovation, said. Read More
Surgery prompted by automobile accidents, combat wounds, cancer treatment and other conditions can lead to bone infections that are difficult to treat and can delay healing until they are resolved. Now, researchers have a developed a double-duty hydrogel that both attacks the bacteria and encourages bone regrowth with a single application containing two active components. The injectable hydrogel, which is a network of cross-linked polymer chains, contains the enzyme lysostaphin and the bone-regenerating protein BMP-2. Read More
Dr. Rowena Jenkins and Dr. Aled Roberts have found that using Manuka honey could offer an antibiotic alternative to treat antimicrobial resistant respiratory infections, particularly deadly bacteria found in Cystic Fibrosis (CF) infections. Using lung tissue from pigs, experts treated grown bacterial infections mimicking those seen in CF patients with Manuka honey. Read More