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Researchers at Binghamton University, State University of New York have developed a method to treat bacterial infections which could result in better wound care. Biofilms are a structured community of bacterial cells that are adherent to inert or living surfaces. What makes these structures special is that living within these biofilm communities makes its resident bacteria resistant to antibiotics. A research team led by Karin Sauer, professor of biological sciences at Binghamton University, demonstrated that two important human pathogens, P. aeruginosa and S. aureus, need pyruvate to form these structured biofilm communities that are inherently resistant to antibiotics. In turn, the research team demonstrated that removal of pyruvate induces a physiological change in biofilm bacteria that has two consequences: 1) it causes them to disassemble the biofilm structure in a process referred to as biofilm dispersion; and 2) it renders biofilm bacteria more susceptible to antibiotics. Read More
We invite all clinicians to participate in our two newest market research studies; SAWC Spring 2019 Conference Feedback, and Wound Care Brand Awareness Study. These two surveys can be found in the Active Surveys section below. Thank you for your participation. Take a Survey
Researchers at Indiana University School of Medicine have found a way to charge up the fight against bacterial infections using electricity. Work conducted in the laboratories of the Indiana Center for Regenerative Medicine and Engineering, Chandan Sen, PhD and Sashwati Roy, PhD has led to the development of a dressing that uses an electric field to disrupt biofilm infection. Their findings were recently published in the journal Annals of Surgery. Bacterial biofilms are thin, slimy films of bacteria that form on some wounds, including burns or post-surgical infections, as well as after a medical device, such as a catheter, is placed in the body. Read More
After injury to periodontal tissues, a sequentially phased healing response is initiated that enables wound closure and partial restoration of tissue structure and function. Wound closure in periodontal tissues involves the tightly regulated coordination of resident cells in epithelial and connective tissue compartments. Multiple cell populations in these compartments synergize their metabolic activities to reestablish a mucosal seal that involves the underlying periodontal connective tissues and the attachment of these tissues to the tooth surface. Read More