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3M Co.'s $6.7 billion purchase of wound-care company Acelity Inc. will be the biggest acquisition in its history. The Maplewood-based 3M, which makes everything from Post-it notes to safety equipment and optical films, said Thursday it is buying San Antonio-based Acelity and its KCI subsidiaries from investment funds Apax Partners, Canada Pension Plan Investment Board and the Public Sector Pension Investment Board. The deal includes the assumption of $2.4 billion of Acelity debt. Read More
Researchers at the University of Wisconsin-Madison have identified specific strains of microbiota in patients with slow-healing diabetic foot ulcers, indicating the microbiomes of foot ulcers could predict clinical outcomes and responses to therapeutic interventions, according to findings published in Cell Host and Microbe. “Our study has shown for the first time that differences at the strain-level within bacterial species can be associated with different outcomes,” Lindsay Kalan, PhD, assistant professor of medical microbiology and immunology at the School of Medicine and Public Health at the University of Wisconsin-Madison, told Endocrine Today. Read More
A team of researchers at Johns Hopkins School of Medicine has developed a gel that, when injected into test animals, allowed new soft tissue to grow—replacing lost tissue. In their paper published in the journal Science Translational Medicine, the group describes their work developing the gel and how well it worked in test rats and rabbits. When a person loses a chunk of soft tissue due to an accident, infection or surgical procedure, surgeons have very few options available to induce the body to regenerate the missing tissue, leaving patients with disfiguring reminders of their loss. In this new effort, the researchers have developed a new gel that shows promise as a soft-tissue regenerative tool. Read More
Extracutaneous infections, particularly ear infections, strep throat and urinary tract infections, have an increased likelihood in patients with atopic dermatitis, according to a literature review. Linda Serrano, MD, and colleagues from Northwestern University Feinberg School of Medicine, reviewed all published observational studies that included controls and evaluated the relationship between atopic dermatitis and bacterial infections. Seven studies, published between 1994 and 2018, were included in the analysis.The researchers identified a higher prevalence of numerous extracutaneous infections across multiple studies. Read More