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“If you’re using electronic cigarettes, or ‘vaping,’ instead of smoking cigarettes, you’re fooling yourself if you think it’s a healthier option,” with regard to wound healing, says Jeffrey Spiegel, a Boston University School of Medicine professor of otolaryngology, head and neck surgery, and chief of Facial Plastic and Reconstructive Surgery at Boston Medical Center. Spiegel is the senior author on a new study, published October 18, 2018, in JAMA Facial Plastic Surgery, that found that electronic cigarettes have virtually the same negative consequences for wound healing as traditional cigarettes. Although electronic cigarettes or “e-cigarettes” have been marketed as a safer alternative to cigarettes, Spiegel says those claims are largely lacking in scientific data. Read More
Imperial researchers have developed a new bioinspired material that interacts with surrounding tissues to promote healing. Materials are widely used to help heal wounds: Collagen sponges help treat burns and pressure sores, and scaffold-like implants are used to repair broken bones. However, the process of tissue repair changes over time, so scientists are looking to biomaterials that interact with tissues as healing takes place. Read More
Antimicrobial peptides play a key role in the innate immunity of all living beings and are bringing new hope in the battle against the escalation of multidrug resistant microbes. The Gomes team looks at new ways to make these peptides useful to fight infections. The Gomes Lab is strongly motivated towards the development of peptide-based approaches against infectious diseases, from both the medicinal chemistry and the biomedical perspectives, for which it has established strong collaborations with groups having complementary skills while sharing this common interest. Peptide-based research by the Gomes team focuses on two main topics: peptide and peptidomimetic derivatives of antimalarial drugs and, more recently, antimicrobial peptides (AMP) and antimicrobial peptides-based materials and formulations for the management of bone and skin infections. Read More
Scientists say, for the first time, they have grown human blood vessels from scratch in the lab that look and behave like the ones in our bodies. "The structure looks the same and the main genes which are expressed in our bodies and in these capillaries are very, very similar," said Josef Penninger, senior author of the new research published last week in the journal Nature. Read More