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Featured Articles

October 22, 2018

Thermal Imaging Improves Diabetes-Related Foot Ulcer Assessment

Thermal imaging can better predict a diabetes related foot ulcer's size and the healing trajectory than conventional methods, Melbourne-led research has found. It could also possibly save money through better targeted treatment. The study, which was the first of its kind, was a collaboration between RMIT University, the University of Melbourne and Austin Health. It used thermal imaging to quantify the size and predict the healing status of recently developed ulcers. Read More

How Fatal Biofilms Form

By severely curtailing the effects of antibiotics, the formation of organized communities of bacterial cells known as biofilms can be deadly during surgeries and in urinary tract infections. Researchers have just come a lot closer to understanding how these biofilms develop, and potentially how to stop them. Biofilms form when bacterial cells gather and develop structures that bond them in a gooey substance. This glue can protect the cells from the outside world and allow them to form complex quasi-organisms. Biofilms can be found almost everywhere, including unwashed shower stalls or the surfaces of lakes. Because the protective shell can keep out potential treatments, biofilms are at their most dangerous when they invade human cells or form on sutures and catheters used in surgeries. Read More

Combined Therapy in the Treatment of Mixed Etiology Leg Ulcer

The most frequent causes of leg ulcers are chronic venous disease (CVD) related mainly to venous hypertension and peripheral arterial disease (PAD) related to disseminated atheromatous lesions in lower limb arteries. In 15%–21% of patients, ulcers of mixed venous-arterial etiology occur, which are usually more resistant for conservative therapy (compression therapy, pharmacotherapy, wearing elastic stockings, leg elevation and massage, change of lifestyle, and regular physical exercises).  Read More

Advancements in Regenerative Strategies Through the Continuum of Burn Care

Currently, multiple strategies exist for the management of burn wounds depending on both the depth and extent of the burn. Burn wound care strategies aim to modulate the inflammatory response, accelerate re-epithelialization, and improve overall wound healing. Furthermore, combinatorial approaches that incorporate cellular-based therapies, pharmacological agents, and biomaterials are utilized to minimize infection and serve as burn wound coverage adjuncts with the goal of restoration of skin function (i.e., barrier, range of motion, sensation, hair and sweat generation, and pigmentation). This review focuses on how therapies for burn injuries are currently being developed to address the array of issues that occur throughout the continuum of burn care. Read More