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Nutrition is a critical component of healing diabetic foot ulcers, particularly as it relates to immune function, malnutrition, glycemic control, and weight loss and weight maintenance. Diabetes educators should include nutrition assessment and intervention as key components of the overall diabetes treatment plan to help patients with diabetic foot ulcers maximize their nutritional status and promote wound healing. Read More
Molecular investigation of wound healing has allowed better understanding about interaction of genes and pathways involved in healing progression. The aim of this study was to prepare magnetic/bacterial nanocellulose (Fe3O4/BNC) nanocomposite films as ecofriendly wound dressing in order to evaluate their physical, cytotoxicity and antimicrobial properties. The molecular study was carried out to evaluate expression of genes involved in healing of wounds after treatment with BNC/Fe3O4 films. Read More
A particular protein that affects the healing of foot and lower leg wounds in people with diabetes has been identified by US researchers. The thrombospondin-2 (TSP2) protein could be targeted to improve treatment for foot ulcers and aid wound healing, researchers say. TSP2 is an integral part of what is known as the extracellular matrix, which behaves like scaffolding in the development of cells. TSP2 is involved in how cells grow, and the research shows that it is a factor that affects how well wounds heal. Read More
Compared with delayed ablation, early endovenous ablation conferred faster healing from leg ulcers due to venous disease and more time free from ulcers, according to findings presented at the Charing Cross International Symposium and published in The New England Journal of Medicine. For the EVRA trial, researchers randomly assigned 450 patients with venous ulcers in the leg to compression therapy and to undergo early endovenous ablation of superficial venous reflux within 2 weeks of randomization or to compression therapy alone with endovenous ablation deferred until the ulcer was healed or after 6 months. The primary outcome was time to ulcer healing. Read More