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Featured Articles

  • March 7, 2017

    Study Explores Links Between Genetic Susceptibility and Heterogeneous Phenotypes of Lymphedema 

    Lymphedema is an abnormal accumulation of lymph fluid in the ipsilateral body area, or upper limb. This remains an ongoing major health problem affecting more than 40 percent of 3.1 million breast cancer survivors in the U.S. Lymphedema following breast cancer surgery is typically considered to be primarily due to the mechanical injury from surgery. However, recent research has found that inflammation-infection and higher body mass index are also main predictors of lymphedema. Read More

    NYU Docs are Using Machine Learning to Stop a Stealthy Disease Before it's Too Late

    There is no cure for Lymphedema, only physical exercises that can keep the symptoms in check. Early detection of the disease would allow for physical therapy that could theoretically stop the disease's progress enough to never allow it to develop. "Machine learning will help us to develop an algorithm to determine a patient's status or predict if they will have a measurable symptom later on, each time the patients enter the data, the algorithm will teach itself. Later on, machine learning will probably help us say which treatment is better for which kind of patients."  Read More

    Two Different Genetic Conditions Can Combine to Cause Severe Infection

    Scientists from the Rockefeller University have led a team of researchers to uncover how two different conditions-a genetic immunodeficiency and delayed acquired immunity--can combine to produce a life-threatening infection. Most of us carry Staphylococcus aureus on our skin and in our nostrils. It can cause minor infections (staph infections), but in some people, it results in severe disease.  Read More

     

  • February 21, 2017

    Tissue-Regenerating Shocks that Heal 

    Shock-wave treatment accelerates impaired wound and injury healing in a very broad range of situations. Evidence shows ESWT treatments are effective at aiding in the repair of tendons, muscle, ligaments, cartilage and even bone. The evidence is so strong that ESWT has become the gold-standard and first-line treatment for several conditions such as shoulder tendinopathies, plantar fasciitis, calcification/spurs, tennis elbow, patellar tendinopathy (jumper’s knee) and Achilles tendinopathy, to name a few. Read More

    Breaking Silos: Effective Wound Healing Means Treatment Across the Continuum

    Around 6.5 million patients in the U.S. suffer from chronic wounds, such as pressure injuries or ulcers. Treatment costs $25 billion each year, representing a sizable and growing problem. Despite the wide impact of chronic wounds, it's rare to see specialized, effective wound care delivered across the care continuum. A chronic non-healing wound is a surrogate marker for illness. These patients require holistic management of their co-morbidities and continuity across care settings.  Read More

    Penn Researchers Find Way to Help Wounds Heal With Less-Visible Scarring  

    After an accident or surgery, the mark left on skin can be a visual reminder of past trauma. Doctors at the University of Pennsylvania have found a way to reduce the visibility of scars. Researchers have discovered a way to make wounds heal differently. Rather than creating scar tissue, the skin regenerates in a way that reducing the visibility of the wound. George Cotsarelis is the chair of the Department of Dermatology at Penn and the principal researcher on the project. Read More

     

  • February 15, 2017

    Underappreciated by Clinicians, Critical Limb Ischemia Has Dire Fallout for Patients 

    Critical limb ischemia (CLI), a condition so elusive that it lacks a consistent definition and doesn't have its own diagnosis code, has a huge impact on patients by way of limb loss and an associated uptick in mortality over follow-up, experts said at a Town Hall devoted to the topic yesterday at the International Symposium on Endovascular Therapy (ISET). Read More

    Tissue Engineering Advance Reduces Heart Failure in Model of Heart Attack

    Researchers have grown heart tissue by seeding a mix of human cells onto a 1-micron-resolution scaffold made with a 3-D printer. The cells organized themselves in the scaffold to create engineered heart tissue that beats synchronously in culture. When the human-derived heart muscle patch was surgically placed onto a mouse heart after a heart attack, it significantly improved heart function and decreased the amount of dead heart tissue. Read More

    Electrical Stimulation Therapy to Promote Healing of Chronic Wounds  

    The overall objective of this study is to identify and appraise all of the existing clinical research literature that has evaluated the effect of electrical stimulation therapy (EST) on wound healing outcomes in adults with various types of chronic wounds. Pooled results from well-conducted SRs provide strong support for the use of EST on various types of chronic wounds and pressure ulcers in particular. Read More

     

  • February 7, 2017

    Alternative to Skin Grafting 

    Skin substitutes hold much potential for wound healing and will offer an alternative to skin grafting, according to a scientist at Sunnybrook Research Institute, Ross Tilley Burn Centre, Toronto, Ontario, Canada. With the aging of the population and the rising incidence in diabetes, there is a growing burden in managing wounds with deficient healing, according to Dr. Amini-Nik. The cost of the treatment of chronic wounds in the United States has been put at more than $25 billion annually. Read More

    New Skin Graft System a Better Fix for Chronic Wounds

    More than six million cases of chronic wounds cost $20 billion each year in the United States. Diabetic ulcers, pressure sores, surgical site wounds and traumatic injuries to high-risk patients account for most wounds that won't heal. However, data indicates that a recently developed skin-graft harvesting system aids in chronic wound recovery and reduces care costs by accelerating the healing process. Read More

    Many Scleroderma Patients Needing Kidney Transplants Do Well, Study Finds  

    Many scleroderma patients show an "excellent" response to a kidney transplant and such surgery should be considered for those with end-stage kidney disease, a study exploring the procedure found. But its researchers also noted that scleroderma patients with lung involvement were the most likely to die after a kidney transplant, indicating that lung health need be included in transplant considerations.  Read More

     

  • January 31, 2017

    Dermatology Stalemate Shows Risks for Patients 

    A months-long stalemate in talks over a new deal between Wayne State University's physician group for dermatologist coverage at Detroit Medical Center hospitals led to a shortfall in the specialists to check out patients' unusual and sometimes life-threatening skin conditions, according to multiple sources. Lack of dermatology consultations - as is true for many other such specialties as neurology, psychiatry and nephrology and is especially acute for Medicaid and uninsured patients - can lead to life-threatening conditions or result in emergency hospitalizations that unnecessarily increase health care costs. Read More

    Calciphylaxis Linked to Low Vitamin K

    Vitamin K deficiency may have a role in the development of calciphylaxis, a rare but frequently fatal condition in dialysis patients, according to newly published study findings. Calciphylaxis is a devastating disease with limited understanding of its pathogenesis and no effective treatment," Dr Nigwekar told Renal & Urology News. "Our present study links vitamin K deficiency with the development of calciphylaxis. This study also identifies matrix gla protein, a vitamin K dependent protein, as a target for future strategies to prevent and/or treat calciphylaxis. Read More

    Ask the Treatment Expert About ... Pressure Injury Assessments  

    Pressure injury risk assessments will assist with patient-centered care planning, improve care plans, provide information related to discharge planning, and, of course, address resident rights. Facility staff should take into account the mobility status of each resident on admission and at specified intervals thereafter, according to the National Pressure Ulcer Advisory Panel. Residents who are admitted unable to walk or requiring assistance to transfer, such as bedfast or chairfast, should be considered at risk for pressure injury and will require a pressure injury prevention focus with care planning. Staff should be informed of residents' mobility status immediately after admission. Read More

     

  • January 24, 2017

    Necrotizing Fasciitis: A Profound Mystery In Medical Microbiology 

    Necrotizing fasciitis, which literally translated means "inflammation of the fascia (connective tissue) causing cell death," is the proper medical term for what is colloquially known as "flesh-eating" disease. The most recent case that made national headlines involved a man who died four days after becoming infected with the ocean-dwelling microbe Vibrio vulnificus. Read More

    Burn Wound Healing: Present Concepts, Treatment Strategies and Future Directions

    Burns are the most extensive forms of soft tissue injuries occasionally resulting in extensive and deep wounds and death. Burns can lead to severe mental and emotional distress, because of excessive scarring and skin contractures. Treatment of burns has always been a difficult medical problem and many different methods have been used to treat such injuries, locally.  Read More

    Space-Age Challenge: Healing Broken Bones, Wounds and Internal Organs  

    Ronke Olabisi, assistant professor in the Department of Biomedical Engineering, and her lab focus on tissue engineering and regenerative medicine to replace or repair bone, skin, muscle and the retina.  Read More