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The market for skin substitutes isn't for the squeamish. Rival products include material from pig intestines, fetal cows, the innermost layer of human amniotic tissue, and cadavers. It can be tough to compare medical outcomes, as clinical trials are small and disease-specific. But generally, because of the viral disease transfer risk, human- and animal-derived products require heavy processing and tend not to work well in infected wounds. That's one of Kerecis's talking points, as the only FDA-approved skin substitute derived from fish: Because of our evolutionary differences, there's less disease risk and therefore less processing required. Read More
Tissue necrosis involves various causes. According to Wound Source, these include infection, toxins, and trauma. In anatomy and physiology, cells that die signal phagocytes to ingest dead cells; however, in tissue necrosis, as per the publication, cells that die due to necrosis fail to signal adjacent phagocytes to ingest the dead cells; this result to the accumulation of dead tissue and cell debris. Other causes of tissue necrosis include infarction, inflammation, poison, and cancer, among others. Read More
Going by the numbers, globally, there are around 415 million people suffering from diabetes; India being the second largest with 69 million. Furthermore, almost 15 percent of diabetics develops an ulcer in their lifetime and around 85 percent faces amputations. These figures were announced at the national level conference on 'Wound Healing' organised by Zen Hospital, Mumbai. To counter the epidemic, most hospitals and institutions have started diabetes management and education programmes. Still, one area that remains grossly neglected and ignored is diabetic foot care. Read More