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Patients who have suffered a length-unstable pilon fracture are routinely staged with an external fixator to stabilize the ankle until the surrounding soft tissue is amenable for surgery, generally between 10 days and 3 weeks. Coupled with delaying surgical intervention, posttraumatic edema also increases the risk of wound complications and postoperative infections. Because pilon fractures have alarmingly high complication rates, it has been suggested that soft tissue management is as important as the bony reconstruction, further highlighting the need to control and reduce swelling in the affected limbs. Read More
More than 25% of seniors age 65 and older have diabetes, and as many as 34% of nursing home residents battle the disease - a rate higher than any other population. Diabetes can damage organs, diminish vascular and arterial health, and cause neuropathy that raises the risk for ulcers, amputations and death. Some studies have shown roughly 1 in 5 infected foot ulcers lead to amputation, and the mortality rate for those with a lower-extremity amputation is just two to five years. Read More
Cell therapy has provided a new avenue for treatment care in diabetic patients and skin repair as a whole. This form of therapy involves modifying white blood cells-the cells that fight infection-to accelerate the healing process. Normally, white blood cells play a vital role in normal wound healing. By maintaining the balance between inflammation and anti-inflammatory reactions, white blood cells promote tissue repair and cellular clean up. By using these modified macrophages, the researchers could heal lesions much more quickly by using a newly developed treatment called adaptive cell transfer. Read More