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Featured Articles

  • January 17, 2018

    Clinical Education Available On-Demand!  "Preventing Surgical Site Infections: Implementing a Multidisciplinary Evidence-Based Strategy."

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    TCMH is Testing Ground for New Wound Therapy Technology

    Mirragen, developed by Missouri Science and Technology student and ceramic engineer Steve Jung, is a bioactive resorbable glass fiber technology that has been found to help wounds heal faster. As a glass fiber, Mirragen can also be used for wounds with challenging geometries. Bioactive glass has been used since the 1960s to grow bone tissue. The silica used in bioactive glass was not a suitable product for growing soft tissue, but Jung used boron in a glass fiber that was found to help heal soft tissue. The borate-based fiber is sturdy and durable for a period of time, but it also breaks down and dissolves as soft tissue heals. Read More

    FDA Grants Marketing Permission for Diabetic Foot Ulcer Treatment Device

    The FDA has permitted the marketing for the first shock-wave device for the use of treating diabetic foot ulcers, according to an agency press release. The device is intended for treatment of chronic, full-thickness diabetic foot ulcers with wound areas no larger than 16 cm2 extending through the epidermis, dermis, tendon or capsule, without bone exposure. The device is an external system that employs pulses of energy to stimulate the wound and is intended for use in adults aged at least 22 years with diabetic foot ulcers of more than 30 days’ duration. The device should be used along with standard care. Read More

    New Molecular Probes to Allow Non-Destructive Analysis of Bioengineered Cartilage

    A new study describes novel probes that enable non-invasive, non-destructive, direct monitoring of the differentiation of mesenchymal stem cells (MSCs) in real-time during the formation of engineered cartilage to replace damaged or diseased tissue. These molecular probes make it possible to assess the quality of the cartilaginous tissue and its suitability for implantation as it is forming, and to make modifications to enhance the multi-step process of MSC differentiation into chondrocytes "on the go". Read More

    An eNose is Able to Sniff out Bacteria that Cause Soft Tissue Infections

    A recent study conducted at the University of Tampere, Tampere University of Technology, Pirkanmaa Hospital District and Fimlab in Finland has concluded that an electronic nose (eNose) can be used to identify the most common bacteria causing soft tissue infections. A recent study conducted at the University of Tampere, Tampere University of Technology, Pirkanmaa Hospital District and Fimlab in Finland has concluded that an electronic nose (eNose) can be used to identify the most common bacteria causing soft tissue infections. Read More

    Science Fiction and Folk Medicine Inspire Novel Wound Dressings

    A relatively inexpensive egg-based formula and a Star Trek-like plasma patch can accelerate healing of serious and chronic wounds. Inspired in part by Star Trek, his favourite show, Dr. Mahrenholz is bringing the sci-fi use of plasma closer to reality by developing an active plasma dressing for treating chronic wounds. But he warns that the current issues we are experiencing with multidrug-resistant bacteria means that we are on the brink of a return to the Middle Ages in terms of our susceptibility to infection. Read More


  • January 10, 2018

    Clinical Education Available On-Demand!  "Preventing Surgical Site Infections: Implementing a Multidisciplinary Evidence-Based Strategy."

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    Specialist says Cryopreserved Tissue is 'Game Changer' for Diabetic Foot Ulcers

    Thanks to a cutting-edge treatment, Anton not only kept her toes, but also maintained normal movement in her foot. Grafix, cryopreserved human placental tissue, was applied to the surface of Anton's wound. She also received hyperbaric oxygen therapy, a medical treatment in which patients breathe 100 percent oxygen while under pressure in a hyperbaric chamber, and wore a total contact cast to maximize offloading. Read More

    Leishmaniasis in Humans: Drug or Vaccine Therapy?

    Leishmania is an obligate intracellular pathogen that invades phagocytic host cells. Approximately 30 different species of Phlebotomine sand flies can transmit this parasite either anthroponotically or zoonotically through their bites. Leishmaniasis has been reported as one of the most dangerous neglected tropical diseases, second only to malaria in parasitic causes of death. People can carry some species of Leishmania for long periods without becoming ill, and symptoms depend on the form of the disease. Read More

    Using Mechanical Forces to Improve Wound Healing

    To most, an operating room and a manufacturing plant are as different as any two places can be. But not to Dennis Orgill. Orgill showed for the first time how to regenerate both the epidermis and the dermis of the skin. He developed a process of infusing a collagen skin graft — known as a scaffold — with healthy cells to promote regeneration. When applied to the wound, the cell-infused scaffold was found to promote healing. Read More

    Low-Intensity Workouts Help Wound Healing for Diabetics

    Low-power exercise may be the key to speeding wound healing rates in patients with diabetes, a new study suggests. Previous research showed moderate-intensity exercise to improve wound healing in both mice and human subjects, but little was known about the impact different intensities could have on healing rates. Read More

    Stop the Splashes, Spills: How Hospitals can Ensure Safe Disposal of Infectious Fluid Waste

    For clinical leaders on the front lines of healthcare, keeping patients and staff safe is the No. 1 priority. The products and practices that are utilized to support infection prevention are the same products and practices that support the safety of the employee as care is given. If facilities focus on one goal and not the other, they won't realize the desired outcome for patients and healthcare workers. It's critical in today's environment to always address both. Read More


  • January 3, 2018

    Clinical Education Available On-Demand!  "Preventing Surgical Site Infections: Implementing a Multidisciplinary Evidence-Based Strategy."

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    Doctors Mend Cancer Wound With World’s Largest Skin Flap

    A team of doctors at KRIMS hospital, Ramdaspeth reconstructed a wound on a young man's face using perhaps world's largest skin flap. The PMMC (pectoralis major myocutaneous) flap, as it is technically called, was taken from right side of patient's chest and used for facial reconstruction on the wound of patient who has cancer in a severe stage. Read More

    A Risk Factor for Drug-Induced Skin Disease Identified

    Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs. DPP-4 inhibitor (DPP-4i) is widely used to treat type 2 diabetes, but increased cases of bullous pemphigoid (BP) have been reported among patients taking the medicine. BP is the most common autoimmune blistering disorder, characterized by itchy reddening of the skin as well as tense blisters over the whole body. Read More

    Researchers Create Unique Bioengineered Organoids for Modeling Colorectal Cancer

    A new study describes a unique bioengineered tissue construct, or organoid, into which colorectal cancer cells are embedded, creating a model of the tumor and surrounding extracellular matrix (ECM). The authors propose that in the future these organoids could be made using a patient's own cells for personalized medicine applications. Read More

    Can Probiotics Help Relieve Atopic Dermatitis Symptoms?

    A new randomized clinical trial published in JAMA Dermatology explores the effectiveness of oral probiotics in treating atopic dermatitis. Atopic dermatitis is a chronic inflammatory skin disease estimated to occur in up to 20% of children around the world. In addition to recurrent bouts of intense inflammation and itching, children with atopic dermatitis are more likely to develop other disorders such as asthma and chronic sinusitis. Read More

    Nurses Should Practice Pressure Ulcer Prevention

    Pressure ulcer or injury prevention remains one of the most common and significant tasks in healthcare for decreasing harm. We would much rather prevent injury than watch a patient live through preventable pain, wounds or diagnoses. A paradigm shift is in progress toward education efforts in communities to help people maintain or achieve healthy lifestyles so preventable conditions are avoided. Read More


  • December 19, 2017

    Clinical Education Available On-Demand!  "Preventing Surgical Site Infections: Implementing a Multidisciplinary Evidence-Based Strategy."

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    The Future of Measuring Patient Safety

    There are at least 57 sessions at the IHI National Forum in Orlando this year that include the words "measure" or "measurement." Clearly there is strong interest in quantifying the results of our efforts to improve the quality of health care. But are we measuring what matters most to keep our patients safe from harm? Or is too much of our attention determined by the hope of incentives and fear of penalties? Read More

    Scientists Discover Metformin As The Optimal Anti-Aging Reagent To Improve Wound Healing

    Cutaneous wounds are one of the most common soft tissue injuries and usually are particularly hard to heal in aging. Recently, a team from Research and Development Center for Tissue Engineering at the Fourth Military Medical University of China identified the topical application of Metformin as the promising pharmacological approach to treat wound defects of both young and aged skin. They hope that this discovery will lead to one feasible cure of nonhealing wounds, particularly in patients with the advancing age. Read More

    Scientists Devise New Treatment for Diabetic Wounds

    Scientists from the Indian Institute of Technology- Madras, Chennai and CSIR- Central Leather Research Institute, Adyar, Chennai have developed a new drug combination to effectively treat diabetic wounds. A dressing of the wounds using the combination drug also revealed and increase in vascularisation- process by which new blood vessels are formed, while also increasing the recruitment of macrophages- a type of white blood cell that protects from infections. Read More

    Doctors Discover New Method to Heal Painful Diabetic Ulcers Using a Jab of 'Muffin Top' Fat

    The dreaded muffin top is the bane of many people's lives - an unsightly roll of flab that spills over the top of trousers or a skirt. But now doctors have discovered an ingenious use for the excess fat - they are using it in injections for painful foot ulcers that are difficult to treat. The technique, which results in rapid healing of the ulcer, has been found to be particularly effective among diabetic patients. Read More

  • December 13, 2017

    Clinical Education Available On-Demand!  "Preventing Surgical Site Infections: Implementing a Multidisciplinary Evidence-Based Strategy."

    View Now

    Research: Prognosis for People with Diabetic Foot Ulcers Worse Than Previously Thought

    The prognosis for people with an infected diabetic foot ulcer is worse than was previously thought, according to new research. More than half the patients in the research study did not see their ulcer heal over a year - and one in seven had to have part or all of their foot amputated. Read More

    Why Simple School Sores Often Lead to Heart and Kidney Disease in Indigenous Children

    Impetigo, also known as school sores, is a highly contagious bacterial skin infection that occurs in children far more frequently than adults. It is one of the most common bacterial infections in children aged two to five years. While the infection itself is treatable, if left untreated it can lead to more serious conditions such as cellulitis (infection of the inner layers of skin) or abscess (painful collections of pus that build up under the skin). It can also progress to kidney disease, or it could cause acute rheumatic fever, which can affect the heart, joints, brain or skin. Read More

    A Dose of Tech to Boost Medical Care

    A medical scanner can assess the severity and depth of wounds in seconds - a task that would take a nurse about half an hour. The Kronikare, as the scanner is called, can also carry out the process with greater accuracy and less pain than if done manually. It uses a smartphone with an off-the-shelf thermal camera to capture the wound, and then interprets it with the help of artificial intelligence. The scanner can determine the size and depth of the wound, the temperature of the affected area and the tissue composition. It can also alert medical staff about any wound complications. Read More

    Treating S. Aureus Skin, Soft Tissue infections

    A pediatric infectious disease physician at Vanderbilt Children's Hospital, and director of the Vanderbilt Vaccine Research Program, told Infectious Diseases in Children that draining the infection is fundamental to treatment in abscesses, often followed by antibiotic treatment after full drainage has occurred. He added that different antibiotics behave differently when treating soft tissue infections."The most important thing is that Staphylococcus aureus-related skin and soft tissue infections are on the decline," he said. Read More

  • December 6, 2017

    Surgery to Create Anuses Inspiring Fistula-Free Generation

    The race is on for a fistula-free generation, but a backlog and new emerging cases of the condition are overwhelming efforts to stem the source. "I cannot say that we are on track," said Iyeme Efem, country manager for Engender Health, which implements a US-funded project Fistula Care Plus to prevent, treat and rehabilitate women and girls living with fistula. Read More

    Mission Trail Hospital Unveils New Diabetes Initiative

    Mission Trail Baptist Hospital recently announced the Amputation Prevention Program (APP) aimed at reducing the number of procedures occurring as a result of complications from diabetes. The APP gives specialists the opportunity to intervene with the patients quicker once the discovery of the lower extremity wound or upon admission. Once the specialist sees the patient within 24 hours, a plan of care is developed for the patient.  Read More

    Probiotic Supplementation Aids Wound Healing in Diabetic Foot Ulcer

    Patients with a diabetic foot ulcer who received probiotic supplementation for 12 weeks experienced faster wound healing coupled with an improved glycemic and lipid profile compared with patients assigned placebo, according to findings from a randomized controlled trial. Probiotics may help to improve inflammatory factors through producing short chain fatty acids in the gut and reducing production of hydrogen peroxide radicals. Read More

    Wound Healing or Regeneration -- the Environment Decides?

    For humans, the loss of limbs is almost always an irreversible catastrophe. Many animals, however, are not only able to heal wounds but even to replace whole body parts. Biologists have now been able to prove for the first time that comb jellyfish can switch between two completely different self-healing processes depending on the environmental conditions. Read More